SLE Lumpus Symptoms

by Dr. Naseem Arshad

September 16, 2024

Introduction to SLE

Our next few posts will focus on Systemic Lupus Erythematosus (SLE). SLE is a complex autoimmune disease. Instead of protecting the body, the immune system mistakenly starts targeting healthy tissues. In this way, the body begins attacking itself and gradually damages its own organs.

Prevalence of SLE

SLE is much more common in women than in men; in fact, it is up to nine times more common in women. This disease typically affects people between the ages of 15 and 40, but it can also occur in very young children or older adults.

Genetic Factors and Triggers

There is often a family history associated with SLE. If someone in your family has SLE, your risk of developing the condition increases. Why does SLE occur? The underlying cause is genetic, meaning certain genetic factors predispose a person to the disease. However, it can also be triggered by external factors such as infections, stress, or exposure to chemicals.

Symptoms of SLE

SLE can affect many parts of the body. Symptoms include persistent fever, fatigue, weakness, loss of appetite, and weight loss. It can affect the hair, sometimes leading to significant hair loss. SLE often causes photosensitivity, resulting in redness or rashes, including the classic butterfly rash on the cheeks and nose.

Skin and Blood Issues

Patients may also develop mouth ulcers, blue or deep red spots on the skin, and other skin issues. SLE can lower the number of red blood cells, white blood cells, and platelets in the body.

Kidney and Cardiovascular Complications

A common complication of SLE is kidney involvement, where protein appears in the urine, blood pressure may rise, and swelling in the legs may develop. Fluid accumulation around the heart or lungs can also occur.

Neurological and Vascular Effects

In addition, SLE can affect the brain and nerves, leading to neurological symptoms. Blood vessels may be involved, and a lack of blood supply to certain areas of the body can cause further complications. In some cases, there may be no visible symptoms, but the kidneys can still be affected, causing silent damage.

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